Mboat7^tm2.1Arai
Targeted Allele Detail

Summary

• Symbol: Mboat7^tm2.1Arai
• Name: membrane bound O-acyltransferase domain containing 7; targeted mutation 2.1, Hiroyuki Arai
• MGI ID: MGI:6467952
• Synonyms: Lpiat1^f
• Gene: Mboat7 Location: Chr7:3680788-3696188 bp, - strand Genetic Position: Chr7, 2.12 cM, cytoband A1
• Alliance: Mboat7^tm2.1Arai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296120
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exon 2-4. The frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:296120)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mboat7 Mutation: 24 strains or lines available

References

• Original: J:296120 Tanaka Y, et al., LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover. Gut. 2020 Apr 6
• All: 2 reference(s)