Eef1d^tm1.1Mkma
Targeted Allele Detail

Summary

• Symbol: Eef1d^tm1.1Mkma
• Name: eukaryotic translation elongation factor 1 delta; targeted mutation 1.1, Masayuki Matsushita
• MGI ID: MGI:6467472
• Synonyms: eEF1BdeltaL-flox
• Gene: Eef1d Location: Chr15:75766643-75781425 bp, - strand Genetic Position: Chr15, 35.05 cM, cytoband E1
• Alliance: Eef1d^tm1.1Mkma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288930
• Parent Cell Line: B6-3i/HK3i (ES Cell)
• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exon 3. The frt-flanked neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:288930)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eef1d Mutation: 38 strains or lines available

References

• Original: J:288930 Kaitsuka T, et al., Deletion of Long Isoform of Eukaryotic Elongation Factor 1Bdelta Leads to Audiogenic Seizures and Aversive Stimulus-Induced Long-Lasting Activity Suppression in Mice. Front Mol Neurosci. 2018;11:358
• All: 1 reference(s)