Ttntm4.1(birA)Mgot
Targeted Allele Detail
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Symbol: |
Ttntm4.1(birA)Mgot |
Name: |
titin; targeted mutation 4.1, Michaal Gotthardt |
MGI ID: |
MGI:6467406 |
Synonyms: |
TiZ-BioIDp |
Gene: |
Ttn Location: Chr2:76534324-76812891 bp, - strand Genetic Position: Chr2, 45.13 cM, cytoband D
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Alliance: |
Ttntm4.1(birA)Mgot page
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Germline Transmission: |
Earliest citation of germline transmission:
J:292446
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Not Specified) |
Mutation: |
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Insertion
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Mutation details: The E.coli bacterial birA (biotin ligase) gene was inserted in exon 28 at the transition of the Z-disc to the I-band and an FRT site, neomycin selection cassette, loxP site and FRT site were inserted downstream of exon 28. Flp-mediated recombination removed the neo cassette.
(J:292446)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ttn Mutation: |
1455 strains or lines available
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Original: |
J:292446 Rudolph F, et al., Deconstructing sarcomeric structure-function relations in titin-BioID knock-in mice. Nat Commun. 2020 Jun 19;11(1):3133 |
All: |
1 reference(s) |
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