Gt(ROSA)26Sor^{tm1(CAG-SNAP*)Pka}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-SNAP*)Pka}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Pekka Katajisto
• MGI ID: MGI:6466976
• Synonyms: Gt(ROSA)26Sor^{tm1(CAG-SNAP-Omp25Cterm)Pka}, MitoSNAP, Tg(Gt(ROSA)26Sor-CAG-LSL-SNAP-tag-Omp25Cterm)Pka
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-SNAP*)Pka} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296065
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: This is a Cre-dependent allele that conditionally expresses a SNAP-tag protein containing 30 amino acid at C-terminus of human SYNJ2BP for mitochondrial localization using the CAG promoter. The SNAP-tag construct consists of an engineered O6-alkylguanine-DNA alkyltransferase that can be specifically and irreversibly labeled with O6-benzylguanine (BG) derivatives. (J:296065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1062 strains or lines available

References

• Original: J:296065 Bui H, et al., Direct Data Submission for two Gt(ROSA)26Sor SNAP alleles. MGI Direct Data Submission. 2020
• All: 1 reference(s)