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Impg2em1Xjz
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Impg2em1Xjz
Name: interphotoreceptor matrix proteoglycan 2; endonuclease-mediated mutation 1, Xianjun Zhu
MGI ID: MGI:6466711
Synonyms: Impg2-, Impg2 Mut1
Gene: Impg2  Location: Chr16:56204313-56273756 bp, + strand  Genetic Position: Chr16, 33.91 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    Exon 2 was targeted with sgRNAs using CRISPR/Cas9 technology, resulting in a 166 bp deletion. (J:295355)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Impg2 Mutation:  40 strains or lines available
References
Original:  J:295355 Xu H, et al., Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice. Hum Mol Genet. 2020 Jun 27;29(10):1624-1634
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory