Otogl^tm1.1Ugds
Targeted Allele Detail

Summary

• Symbol: Otogl^tm1.1Ugds
• Name: otogelin-like; targeted mutation 1.1, Unite de Genetique des Deficits Sensoriels
• MGI ID: MGI:6466541
• Synonyms: Otogl^fl
• Gene: Otogl Location: Chr10:107596392-107747995 bp, - strand Genetic Position: Chr10, 56.11 cM
• Alliance: Otogl^tm1.1Ugds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282794
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 5 and 6 were flanked by loxP sites and an frt-flanked neomycin selection cassette. The neomycin selection cassette was deleted via FLP-mediated recombination leaving loxP siites flanking exons 5 and 6. (J:282794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Otogl Mutation: 136 strains or lines available

References

• Original: J:282794 Avan P, et al., Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25948-25957
• All: 1 reference(s)