Cxxc1^em1.1Ptkv
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cxxc1^em1.1Ptkv
• Name: CXXC finger protein 1; endonuclease-mediated mutation 1.1, Petko Petkov
• MGI ID: MGI:6466533
• Synonyms: Cxxc1^delta
• Gene: Cxxc1 Location: Chr18:74349283-74354564 bp, + strand Genetic Position: Chr18, 50.7 cM
• Alliance: Cxxc1^em1.1Ptkv page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-Cas9 genome editing technology was used to insert loxP sites flanking exons 2 and 3. Cre-mediated recombination in the germline resulted in the deletion of the flanked exons. (J:267768)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxxc1 Mutation: 27 strains or lines available

References

• Original: J:267768 Tian H, et al., CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse. PLoS Genet. 2018 Oct;14(10):e1007657
• All: 1 reference(s)