Adtrptm1.2Clu
Targeted Allele Detail
|
Symbol: |
Adtrptm1.2Clu |
Name: |
androgen dependent TFPI regulating protein; targeted mutation1.2, Cristina Lupu |
MGI ID: |
MGI:6460466 |
Synonyms: |
Adtrpfl |
Gene: |
Adtrp Location: Chr13:41916621-42001092 bp, - strand Genetic Position: Chr13, 20.61 cM
|
Alliance: |
Adtrptm1.2Clu page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:295059
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
C57BL/6
|
|
Allele Type: |
|
Targeted (Conditional ready) |
Mutation: |
|
Insertion
|
|
|
Mutation details: A loxP site was inserted into intron 1, a second loxP site and an FRT site flanked neomycin resistance gene cassette into intron 2, a third loxP site into intron 4, and a fourth loxP site and an FRT site flanked hygromycin resistance gene cassette into intron 5. Subsequent ROSA26-Flpe-mediated recombination deleted the neo and hygro cassettes, leaving a conditional-ready allele with exons 1, 2-4 and 5 floxed.
(J:295059)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Adtrp Mutation: |
21 strains or lines available
|
|
Original: |
J:295059 Patel MM, et al., Role of ADTRP (Androgen-Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function. J Am Heart Assoc. 2018 Nov 20;7(22):e010690 |
All: |
1 reference(s) |
|