Klra13-ps^em1Wyok
Endonuclease-mediated Allele Detail

Summary

• Symbol: Klra13-ps^em1Wyok
• Name: killer cell lectin-like receptor subfamily A, member 13, pseudogene; endonuclease-mediated mutation 1, Wayne Yokoyama
• MGI ID: MGI:6460362
• Synonyms: Ly49M^-
• Gene: Klra13-ps Location: Chr6:130268124-130283391 bp, - strand Genetic Position: Chr6, 63.44 cM
• Alliance: Klra13-ps^em1Wyok page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was targeted using sgRNAs with CRISPR/Cas9 technology. A number of different out-of-frame insertion/deletion alleles were created, named M1 (GTCTCCT deletion), M3 (TC deletion), M7 (T insertion) and M8 (GAGGCTTCCCTGTCTC deletion). (J:295190)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klra13-ps Mutation: 8 strains or lines available

References

• Original: J:295190 Parikh BA, et al., Control of Viral Infection by Natural Killer Cell Inhibitory Receptors. Cell Rep. 2020 Jul 28;32(4):107969
• All: 1 reference(s)