Gpr146^em2Ccwn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr146^em2Ccwn
• Name: G protein-coupled receptor 146; endonuclease-mediated mutation 2, Chad A Cowan
• MGI ID: MGI:6460323
• Gene: Gpr146 Location: Chr5:139363452-139382170 bp, + strand Genetic Position: Chr5, 78.49 cM, cytoband G1
• Alliance: Gpr146^em2Ccwn page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed the open reading frame. (J:289767)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr146 Mutation: 23 strains or lines available

References

• Original: J:289767 Yu H, et al., GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis. Cell. 2019 Nov 27;179(6):1276-1288.e14
• All: 1 reference(s)