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Ros1em1Osb
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Ros1em1Osb
Name: Ros1 proto-oncogene; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI ID: MGI:6460274
Gene: Ros1  Location: Chr10:51921817-52071340 bp, - strand  Genetic Position: Chr10, 26.18 cM
Mutation
origin
Strain of Origin:  (C57BL/6NJcl x DBA/2NJcl)F2
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR-targeting of exon 18 through exon 35 deleted 52, 533 bp. (J:290452)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ros1 Mutation:  87 strains or lines available
References
Original:  J:290452 Kiyozumi D, et al., NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Science. 2020 Jun 5;368(6495):1132-1135
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/03/2022
MGI 6.21
The Jackson Laboratory