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Tg(Aif1-tTA)75Kftnk
Transgene Detail
Summary
Symbol: Tg(Aif1-tTA)75Kftnk
Name: transgene insertion 75, Kenji Tanaka
MGI ID: MGI:6460099
Transgene: Tg(Aif1-tTA)75Kftnk  Location: unknown  
Alliance: Tg(Aif1-tTA)75Kftnk page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsA modified 2 kb of the mouse promoter drives microglia-specific expression of a mammalianized tetracycline transactivator (tTA). The modification prevents fusion between the mouse sequence and the mammalianized tTA. Lines 54 and 75 were generated. (J:186771)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:186771 Tanaka KF, et al., Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep. 2012 Aug 30;2(2):397-406
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory