Tg(Thy1/THY1)T16Gsv
Transgene Detail
|
Symbol: |
Tg(Thy1/THY1)T16Gsv |
Name: |
transgene insertion T16, Frank Grosveld |
MGI ID: |
MGI:6459738 |
Synonyms: |
T16 |
Transgene: |
Tg(Thy1/THY1)T16Gsv Location: unknown
|
Alliance: |
Tg(Thy1/THY1)T16Gsv page
|
|
|
Transgene Type: |
|
Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
|
Insertion
|
|
|
Tg(Thy1/THY1)T16Gsv expresses
2 genes
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
mouse |
Thy1 (MGI:98747) |
|
hybrid of mouse and human sequences |
human |
THY1 (7070) |
|
hybrid of mouse and human sequences |
|
|
|
Mutation details: This transgene consists of a hybrid Thy1 gene in which a 5.7 kb EcoRI-ApaI mouse Thy1a (Thy1.1) gene fragment containing the first 4 exons (including exons 1a and 1b) and part of exon 4 are fused to a 3.4 kb ApaI-EcoRI human THY1 DNA sequence containing the remaining noncoding part of exon 4 plus 3' human flanking sequence. The mature protein resulting from this transgene is completely Thy1a.
(J:133943)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
Original: |
J:294753 Ebrahim H, et al., Antibody induced injury to podocytes with proteinuria and foot process swelling in a transgenic (T16) mouse. Int J Exp Pathol. 1999 Apr;80(2):77-86 |
All: |
2 reference(s) |
|