Vps4a^tm1.2Thkn
Targeted Allele Detail

Summary

• Symbol: Vps4a^tm1.2Thkn
• Name: vacuolar protein sorting 4A; targeted mutation 1.2, Thomas Klein
• MGI ID: MGI:6459252
• Gene: Vps4a Location: Chr8:107757901-107772392 bp, + strand Genetic Position: Chr8, 53.53 cM, cytoband D
• Alliance: Vps4a^tm1.2Thkn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236761
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were floxed. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 2 and 3. (J:236761)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vps4a Mutation: 15 strains or lines available

References

• Original: J:236761 Drusenheimer N, et al., The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015 Dec;11(12):e1005749
• All: 1 reference(s)