Tg(Cdx2-Tgfbr1*)#Mllo
Transgene Detail

Summary

• Symbol: Tg(Cdx2-Tgfbr1*)#Mllo
• Name: transgene insertion, Moises Mallo
• MGI ID: MGI:6458913
• Synonyms: Cdx2P-Alk5^CA
• Transgene: Tg(Cdx2-Tgfbr1*)#Mllo Location: unknown
• Alliance: Tg(Cdx2-Tgfbr1*)#Mllo page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Cdx2-Tgfbr1*)#Mllo expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tgfbr1 (MGI:98728)	modified Tgfbr1 cDNA (threonine to aspartic acid, p.T200D) that codes for a constitutively active form

• Mutation details: An enhancer element from the Cdx2 gene that drives expression in the posterior epiblast and the primitive streak drives the expression of a modified Tgfbr1 cDNA (threonine to aspartic acid, p.T200D) that codes for a constitutively active form. (J:198634)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:198634 Jurberg AD, et al., Switching axial progenitors from producing trunk to tail tissues in vertebrate embryos. Dev Cell. 2013 Jun 10;25(5):451-62
• All: 2 reference(s)