Rec8^em1Jw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rec8^em1Jw
• Name: REC8 meiotic recombination protein; endonuclease-mediated mutation 1, Jeremy Wang
• MGI ID: MGI:6455736
• Gene: Rec8 Location: Chr14:55855494-55862852 bp, + strand Genetic Position: Chr14, 28.19 cM
• Alliance: Rec8^em1Jw page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed exons 2 through 19. (J:289957)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rec8 Mutation: 25 strains or lines available

References

• Original: J:289957 Guan Y, et al., SKP1 drives the prophase I to metaphase I transition during male meiosis. Sci Adv. 2020 Mar;6(13):eaaz2129
• All: 2 reference(s)