Gipr^tm1.1Nina
Targeted Allele Detail

Summary

• Symbol: Gipr^tm1.1Nina
• Name: gastric inhibitory polypeptide receptor; targeted mutation 1,1, Nobuya Inagaki
• MGI ID: MGI:6453609
• Synonyms: Gipr^fl
• Gene: Gipr Location: Chr7:18889986-18900052 bp, - strand Genetic Position: Chr7, 9.46 cM
• Alliance: Gipr^tm1.1Nina page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246076
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites flank exons 2-7. An frt-flanked neomycin selection cassette in intron 7 was removed via FLP-mediated recombination. (J:246076)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gipr Mutation: 31 strains or lines available

References

• Original: J:246076 Joo E, et al., Inhibition of Gastric Inhibitory Polypeptide Receptor Signaling in Adipose Tissue Reduces Insulin Resistance and Hepatic Steatosis in High-Fat Diet-Fed Mice. Diabetes. 2017 Apr;66(4):868-879
• All: 1 reference(s)