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Ace2em2(ACE2)Gpt
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Ace2em2(ACE2)Gpt
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
MGI ID: MGI:6452442
Synonyms: Ace2em1Cin(hACE2-stop)
Gene: Ace2  Location: ChrX:162922338-162971414 bp, + strand  Genetic Position: ChrX, 76.12 cM, cytoband F5
Mutation
origin
Strain of Origin:  C57BL/6JGpt
Mutation
description
Allele Type:    Endonuclease-mediated (Inserted expressed sequence)
Mutation:    Undefined
 
Ace2em2(ACE2)Gpt expresses 1 gene
 
Mutation detailsCRISPR/Cas9 technology inserted a chimeric coding sequence of the extracellular region of human ACE2 fused with the intracellular region and the transmembrane region of mouse Ace2 and stop codon into exon 1 of the gene (ENSMUST00000073973.10). (J:293217)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ace2 Mutation:  23 strains or lines available
References
Original:  J:293217 GemPharmatech, GemPharmatech website. website. 2020;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/07/2021
MGI 6.17
The Jackson Laboratory