Cnr2^tm2.1Zim
Targeted Allele Detail

Summary

• Symbol: Cnr2^tm2.1Zim
• Name: cannabinoid receptor 2; targeted mutation 2.1, Andreas Zimmer
• MGI ID: MGI:6451134
• Gene: Cnr2 Location: Chr4:135622705-135647518 bp, + strand Genetic Position: Chr4, 68.01 cM
• Alliance: Cnr2^tm2.1Zim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239575
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Two loxP sites were inserted into the gene flanking the coding exon 2 by homologous recombination. An FRT-flanked neo selection cassette was also inserted upstream of the loxP site in the 3'untranslated region. FLP-mediated recombination removed the selection cassette in the germline. (J:239575)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnr2 Mutation: 27 strains or lines available

References

• Original: J:239575 Stempel AV, et al., Cannabinoid Type 2 Receptors Mediate a Cell Type-Specific Plasticity in the Hippocampus. Neuron. 2016 May 18;90(4):795-809
• All: 1 reference(s)