Fadd^em1Hbz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fadd^em1Hbz
• Name: Fas associated via death domain; endonuclease-mediated mutation 1, Haibing Zhang
• MGI ID: MGI:6449654
• Gene: Fadd Location: Chr7:144132060-144136178 bp, - strand Genetic Position: Chr7, 88.85 cM
• Alliance: Fadd^em1Hbz page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• A 100-bp deletion was introduced into exon 1 by CRIPSR/Cas9 genome editing technology. (J:280177)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fadd Mutation: 20 strains or lines available

References

• Original: J:280177 Fa Z, et al., RIPK3/Fas-Associated Death Domain Axis Regulates Pulmonary Immunopathology to Cryptococcal Infection Independent of Necroptosis. Front Immunol. 2017;8:1055
• All: 2 reference(s)