Cdkn2aem2Hwl
Endonuclease-mediated Allele Detail
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Symbol: |
Cdkn2aem2Hwl |
Name: |
cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 2, Han-Woong Lee |
MGI ID: |
MGI:6449246 |
Synonyms: |
B6-p16Ink4a KO |
Gene: |
Cdkn2a Location: Chr4:89192710-89212856 bp, - strand Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
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Alliance: |
Cdkn2aem2Hwl page
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Allele Type: |
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Endonuclease-mediated (Modified isoform(s), Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: A seven-nucleotide deletion, predicted to produce abnormal 16 AAs before a premature termination codon, was generated by TALEN mediated excision in the C57BL/6J strain.
(J:281699)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cdkn2a Mutation: |
62 strains or lines available
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Original: |
J:281699 Park BM, et al., Generation of knockout mouse models of cyclin-dependent kinase inhibitors by engineered nuclease-mediated genome editing. Lab Anim Res. 2018 Dec;34(4):264-269 |
All: |
1 reference(s) |
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