Bin1^em1Adiuj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bin1^em1Adiuj
• Name: bridging integrator 1; endonuclease-mediated mutation 1, MODEL-AD Center
• MGI ID: MGI:6446961
• Gene: Bin1 Location: Chr18:32510283-32568790 bp, + strand Genetic Position: Chr18, 18.01 cM
• Alliance: Bin1^em1Adiuj page

Mutation origin

• Strain of Origin: B6.Cg-Apoe^{tm1.1(APOE*4)Adiuj} App^em1Adiuj Trem2^em1Adiuj/J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutations: Insertion, Single point mutation
• Mutation details: Plasmids encoding a single guide RNA are designed to introduce a C-to-A point mutation in the promoter flanking region (between exon 1 and exon 2). (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bin1 Mutation: 27 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)