Ptk2b^em1Adiuj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ptk2b^em1Adiuj
• Name: PTK2 protein tyrosine kinase 2 beta; endonuclease-mediated mutation 1, MODEL-AD Center
• MGI ID: MGI:6446957
• Gene: Ptk2b Location: Chr14:66390706-66518501 bp, - strand Genetic Position: Chr14, 34.36 cM
• Alliance: Ptk2b^em1Adiuj page

Mutation origin

• Strain of Origin: B6.Cg-Apoe^{tm1.1(APOE*4)Adiuj} App^em1Adiuj Trem2^em1Adiuj/J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutations: Insertion, Single point mutation
• Mutation details: Plasmids encoding a single guide RNA are designed to introduce a C-to-A point mutation in the promoter flanking region (intron 5) of the Ptk2b gene. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ptk2b Mutation: 55 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)