Pilra^em1Adiuj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pilra^em1Adiuj
• Name: paired immunoglobin-like type 2 receptor alpha; endonuclease-mediated mutation 1, MODEL-AD Center
• MGI ID: MGI:6444737
• Synonyms: Pilra^G85R
• Gene: Pilra Location: Chr5:137820214-137834540 bp, - strand Genetic Position: Chr5, 76.77 cM
• Alliance: Pilra^em1Adiuj page

Mutation origin

• Strain of Origin: B6.Cg-Apoe^{tm1.1(APOE*4)Adiuj} App^em1Adiuj Trem2^em1Adiuj/J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• CRISPR/Cas9 genome editing is used to edit amino acids at positions 85-88 from GEFI to RQSF. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pilra Mutation: 24 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)