Sumf1^{tm1c(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Sumf1^{tm1c(KOMP)Wtsi}
• Name: sulfatase modifying factor 1; targeted mutation 1c, Wellcome Trust Sanger Institute
• MGI ID: MGI:6438232
• Gene: Sumf1 Location: Chr6:108083989-108162543 bp, - strand Genetic Position: Chr6, 49.71 cM
• Alliance: Sumf1^{tm1c(KOMP)Wtsi} page

Mutation origin

• Mutant Cell Line: EPD0199_1_C01
• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at a position on Chromosome 6 downstream of exon 3 of the gene. The cassette is composed of an FRT site followed by a lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance (neo) cassette under the control of the human beta-actin promoter, an SV40 polyadenylation signal, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 4. Flp-mediated recombination removed the FRT-flanked lacZ and neo cassette. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sumf1 Mutation: 33 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)