Hscb^{tm1c(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Hscb^{tm1c(EUCOMM)Hmgu}
• Name: HscB iron-sulfur cluster co-chaperone; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6438165
• Synonyms: Hscb^fl
• Gene: Hscb Location: Chr5:110976936-110987643 bp, - strand Genetic Position: Chr5, 53.72 cM
• Alliance: Hscb^{tm1c(EUCOMM)Hmgu} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:290037
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The L1L2_Bact_P cassette was inserted at position 110985016 of Chromosome 5 upstream of exon 3 (Build GRCm39).The targeting construct contains a loxP site in intron 2 and a second loxP site in intron 3 followed by a FRT-flanked neomycin cassette. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:290037)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hscb Mutation: 23 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 2 reference(s)