Tg(Camk2a-PLA2G4A)31Mrl
Transgene Detail

Summary

• Symbol: Tg(Camk2a-PLA2G4A)31Mrl
• Name: transgene insertion 31, Merck Research Laboratory
• MGI ID: MGI:6434525
• Transgene: Tg(Camk2a-PLA2G4A)31Mrl Location: unknown
• Alliance: Tg(Camk2a-PLA2G4A)31Mrl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Camk2a-PLA2G4A)31Mrl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PLA2G4A (5321)

  Pla2g4a

  (MGI:1195256)

• Mutation details: The transgenic construct contains 5 the 8.5 kb mouse CaM-kinase II alpha chain (mCamk2a) promoter fragment, an 850 bp DNA fragment containing the human beta-globin intron 2, and 2247bp ORF of human PLA2G4A cDNA (GenBank Acc# NM_024420), followed by 221bp of SV40 poly A sequence at the 3 end in a pGL3 vector backbone (Promega). A consensus KOZAK sequence was added upstream of the starter ATG. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)