Tyk2^tm1.2Mrl
Targeted Allele Detail

Summary

• Symbol: Tyk2^tm1.2Mrl
• Name: tyrosine kinase 2; targeted mutation 1.2, Merck Research Laboratory
• MGI ID: MGI:6434088
• Gene: Tyk2 Location: Chr9:21015364-21042539 bp, - strand Genetic Position: Chr9, 7.71 cM, cytoband A3
• Alliance: Tyk2^tm1.2Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4 to 6 was flanked by loxP sites (size of loxP-flanked region: 2.3 kb). The conditional KO allele was obtained after Flp-mediated removal of the selection marker. Cre-mediated recombination removed exons 4 through 6. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tyk2 Mutation: 69 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)