Cyp8b1^tm1.2Mrl
Targeted Allele Detail

Summary

• Symbol: Cyp8b1^tm1.2Mrl
• Name: cytochrome P450, family 8, subfamily b, polypeptide 1; targeted mutation 1.2, Merck Research Laboratory
• MGI ID: MGI:6431411
• Gene: Cyp8b1 Location: Chr9:121743422-121745371 bp, - strand Genetic Position: Chr9, 72.73 cM, cytoband F4
• Alliance: Cyp8b1^tm1.2Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and 1.9 kb of sequence upstream of exon 1 were floxed. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 1 and the upstream sequence. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cyp8b1 Mutation: 32 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)