Hdac11^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hdac11^em1Cya
• Name: histone deacetylase 11; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6429836
• Synonyms: Hdac11^em1Cgen, Hdac1^em1cyagen
• Gene: Hdac11 Location: Chr6:91133652-91151674 bp, + strand Genetic Position: Chr6, 40.38 cM
• Alliance: Hdac11^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exons 3-6 were targeted, (J:271469)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hdac11 Mutation: 19 strains or lines available

References

• Original: J:271469 Fan XD, et al., HDAC11 deletion reduces fructose-induced cardiac dyslipidemia, apoptosis and inflammation by attenuating oxidative stress injury. Biochem Biophys Res Commun. 2018 Sep 5;503(2):444-451
• All: 2 reference(s)