Cntn2^tm1.2Ajaw
Targeted Allele Detail

Summary

• Symbol: Cntn2^tm1.2Ajaw
• Name: contactin 2; targeted mutation 1.2, Alexander Jaworski
• MGI ID: MGI:6423508
• Synonyms: TAG-1 KO
• Gene: Cntn2 Location: Chr1:132437163-132470989 bp, - strand Genetic Position: Chr1, 57.42 cM
• Alliance: Cntn2^tm1.2Ajaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:287691
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: LoxP sites were inserted into non-conserved intronic regions 553bp upstream and 530bp downstream of exon 2. The 3' LoxP site was preceded by a Frt-flanked neomycin (Neo) cassette. Exon 2 and the neomycin selection cassette were removed in the germline via FLP and Cre-mediated recombination. (J:287691)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cntn2 Mutation: 57 strains or lines available

References

• Original: J:287691 Suter TACS, et al., TAG-1 Multifunctionality Coordinates Neuronal Migration, Axon Guidance, and Fasciculation. Cell Rep. 2020 Jan 28;30(4):1164-1177.e7
• All: 1 reference(s)