Apex1^tm1Ernst
Targeted Allele Detail

Summary

• Symbol: Apex1^tm1Ernst
• Name: apurinic/apyrimidinic endonuclease 1; targeted mutation 1, Peter Ernst
• MGI ID: MGI:6416531
• Gene: Apex1 Location: Chr14:51162425-51164596 bp, + strand Genetic Position: Chr14, 26.3 cM, cytoband C3
• Alliance: Apex1^tm1Ernst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:350733
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutation: Not Specified
• No details provided

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Apex1 Mutation: 13 strains or lines available

References

• Original: J:350733 Rios-Covian D, et al., A Novel Hypomorphic Apex1 Mouse Model Implicates Apurinic/Apyrimidinic Endonuclease 1 in Oxidative DNA Damage Repair in Gastric Epithelial Cells. Antioxid Redox Signal. 2023 Jan;38(1-3):183-197
• All: 1 reference(s)