Rnf2^tm2.1Hgu
Targeted Allele Detail

Summary

• Symbol: Rnf2^tm2.1Hgu
• Name: ring finger protein 2; targeted mutation 2.1, MRC Human Genetics Unit
• MGI ID: MGI:6414569
• Gene: Rnf2 Location: Chr1:151345159-151376562 bp, - strand Genetic Position: Chr1, 64.15 cM
• Alliance: Rnf2^tm2.1Hgu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283578
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 3. A floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 and the selection cassette. (J:283578)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf2 Mutation: 35 strains or lines available

References

• Original: J:283578 Illingworth RS, et al., The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development. Genes Dev. 2015 Sep 15;29(18):1897-902
• All: 1 reference(s)