Sf3b2^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sf3b2^em1(IMPC)Tcp
• Name: splicing factor 3b, subunit 2; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6414540
• Gene: Sf3b2 Location: Chr19:5323960-5345483 bp, - strand Genetic Position: Chr19, 4.29 cM, cytoband A
• Alliance: Sf3b2^em1(IMPC)Tcp page
• IMPC: Sf3b2 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project TCPR1507 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GGACCAGGCCTCAGCTTATA targeting the 5' side and ACTTAAGTCTTCATCCAAGT targeting the 3' side of a critical region. This resulted in a 493-bp del, Chr19: 5287369-5287861 (GRCm38). (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sf3b2 Mutation: 26 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 1 reference(s)