Tfrc^Rbc5
Chemically induced Allele Detail

Summary

• Symbol: Tfrc^Rbc5
• Name: transferrin receptor; red blood cell mutant 5
• MGI ID: MGI:6406245
• Synonyms: Tfrc^L642R
• Gene: Tfrc Location: Chr16:32427738-32451612 bp, + strand Genetic Position: Chr16, 23.06 cM
• Alliance: Tfrc^Rbc5 page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to G point mutation that results in the amino acid substitution of arginine with leucine at position 642 (L642R). (J:285514)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfrc Mutation: 61 strains or lines available

References

• Original: J:285514 Conway AJ, et al., Characterization of Tfrc-mutant mice with microcytic phenotypes. Blood Adv. 2018 Aug 14;2(15):1914-1922
• All: 1 reference(s)