Gt(ROSA)26Sor^tm596Arte
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm596Arte
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 596, TaconicArtemis
• MGI ID: MGI:6403298
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm596Arte page

Mutation origin

• Germline Transmission: Not Specified
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (RMCE-ready)
• Mutation: Insertion
• Mutation details: An RMCE-ready ES cell line was generated to contain inserted at the locus a splice acceptor, F3 site, hypgromycin resistance cassette, LacZ reporter gene, polyadenylation site, and FRT site. (J:184973)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

Notes

ES cells = Art B6 RMCE 101.2 (genetic background C57BL/6NTac)

References

• Original: J:184973 Gafni J, et al., Caspase-6 Activity in a BACHD Mouse Modulates Steady-State Levels of Mutant Huntingtin Protein But Is Not Necessary for Production of a 586 Amino Acid Proteolytic Fragment. J Neurosci. 2012 May 30;32(22):7454-7465
• All: 3 reference(s)