Fmr1tm1Drnl
Targeted Allele Detail
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Symbol: |
Fmr1tm1Drnl |
Name: |
fragile X messenger ribonucleoprotein 1; targeted mutation 1, Jennifer Darnell |
MGI ID: |
MGI:6393408 |
Synonyms: |
Fmr1cTag |
Gene: |
Fmr1 Location: ChrX:67722147-67761569 bp, + strand Genetic Position: ChrX, 34.83 cM
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Alliance: |
Fmr1tm1Drnl page
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Germline Transmission: |
Earliest citation of germline transmission:
J:285231
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Parent Cell Line: |
CY2.4 (ES Cell)
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Strain of Origin: |
B6(Cg)-Tyrc-2J
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Allele Type: |
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Targeted (Conditional ready, Reporter) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 17. The targeting vector also inserted downstream of the endogenous exon 17 a neomycin resistance cassette, loxP site and modified exon 17 with an inframe AcGFP reporter gene downstream of the coding sequence with the untranslated sequence preserved.
(J:285231)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Fmr1 Mutation: |
28 strains or lines available
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Original: |
J:285231 Van Driesche SJ, et al., FMRP binding to a ranked subset of long genes is revealed by coupled CLIP and TRAP in specific neuronal cell types. bioRxiv. 2019; |
All: |
3 reference(s) |
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