Kif1b^tm2Noh
Targeted Allele Detail

Summary

• Symbol: Kif1b^tm2Noh
• Name: kinesin family member 1B; targeted mutation 2, Nobutaka Hirokawa
• MGI ID: MGI:6392884
• Synonyms: Kif1beta-EGFP
• Gene: Kif1b Location: Chr4:149260776-149392150 bp, - strand Genetic Position: Chr4, 79.05 cM, cytoband E
• Alliance: Kif1b^tm2Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265837
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An EGFP gene was inserted at the 3'end of the coding region, followed by a recombinase-flnaked neomycin selection cassette. (J:265837)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif1b Mutation: 128 strains or lines available

References

• Original: J:265837 Xu F, et al., KIF1Bbeta mutations detected in hereditary neuropathy impair IGF1R transport and axon growth. J Cell Biol. 2018 Oct 1;217(10):3480-3496
• All: 1 reference(s)