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Tg(Nefl-App*)G2Lfa
Transgene Detail
Summary
Symbol: Tg(Nefl-App*)G2Lfa
Name: transgene insertion 1, Frank LaFerla
MGI ID: MGI:6392314
Transgene: Tg(Nefl-App*)G2Lfa  Location: unknown  
Alliance: Tg(Nefl-App*)G2Lfa page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA 1.8 Kb mouse Nefl (neurofilament, light polypeptide) promoter drives the expression of a rat cDNA encoding the 42 amino acid ABeta peptide of App. Lines G2, J3 and J4 were generated. (J:42427)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:42427 LaFerla FM, et al., The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat Genet. 1995 Jan;9(1):21-30
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory