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Fancd2em1Tzh
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Fancd2em1Tzh
Name: Fanconi anemia, complementation group D2; endonuclease-mediated mutation 1, Tingting Zhang
MGI ID: MGI:6392092
Gene: Fancd2  Location: Chr6:113531682-113597017 bp, + strand  Genetic Position: Chr6, 52.78 cM, cytoband E3
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/Cas9 technology generated a 7 bp deletion (ACACTGA) in exon 5. (J:284566)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fancd2 Mutation:  53 strains or lines available
References
Original:  J:284566 Yang Q, et al., Severe Fanconi Anemia phenotypes in Fancd2 depletion mice. Biochem Biophys Res Commun. 2019 Jun 30;514(3):713-719
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory