Zic4^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zic4^em1(IMPC)H
• Name: zinc finger protein of the cerebellum 4; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6390533
• Gene: Zic4 Location: Chr9:91247636-91271404 bp, + strand Genetic Position: Chr9, 48.26 cM
• Alliance: Zic4^em1(IMPC)H page
• IMPC: Zic4 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele was generated at Medical Research Council Harwell using Cas9 and guides with spacer sequences CATGCCGCCATAACCGTGCA and TCATGCCGCCATAACCGTGC that targeted exon(s) ENSMUSE00000531098.3 ENSMUSE00000934208.2. This resulted in deletion(s) of 5 bp (location: Chr9:91261050-91261054; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Zic4 Mutation: 26 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)