Pcdh15^tm3.1Ugds
Targeted Allele Detail

Summary

• Symbol: Pcdh15^tm3.1Ugds
• Name: protocadherin 15; targeted mutation 3.1, Unite de Genetique des Deficits Sensoriels
• MGI ID: MGI:6389239
• Synonyms: Pcdh15 ex-39fl
• Gene: Pcdh15 Location: Chr10:72935174-74485569 bp, + strand Genetic Position: Chr10, 37.43 cM
• Alliance: Pcdh15^tm3.1Ugds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283661
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 39 was floxed. Flp-mediated recombination removed the neomycin selection cassette. Removal of exon 39 by cre-recombinase results in loss of PCDH15-CD3 while PCDH15-CD1 and PCDH15-CD2 are not altered (J:283661)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdh15 Mutation: 135 strains or lines available

References

• Original: J:283661 Pepermans E, Direct data submission of two Pcdh15 floxed alleles from Unite de Genetique des Deficits Sensoriels. MGI Direct Data Submission. 2020
• All: 2 reference(s)