Vmp1^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Vmp1^tm1.1Arte
• Name: vacuole membrane protein 1; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6386774
• Synonyms: Vmp1^flox
• Gene: Vmp1 Location: Chr11:86474691-86574662 bp, - strand Genetic Position: Chr11, 51.82 cM, cytoband C
• Alliance: Vmp1^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:280741
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and left exons 3 adn 4 floxed. (J:280741)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vmp1 Mutation: 37 strains or lines available

References

• Original: J:280741 Morishita H, et al., A critical role of VMP1 in lipoprotein secretion. Elife. 2019 Sep 17;8:e48834
• All: 4 reference(s)