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Sv2aem1(IMPC)H
Endonuclease-mediated Allele Detail
Summary
Symbol: Sv2aem1(IMPC)H
Name: synaptic vesicle glycoprotein 2a; endonuclease-mediated mutation 1, Harwell
MGI ID: MGI:6386303
Gene: Sv2a  Location: Chr3:96088543-96102499 bp, + strand  Genetic Position: Chr3, 41.65 cM, cytoband F2
Alliance: Sv2aem1(IMPC)H page
IMPC: Sv2a gene page
Mutation
origin
Strain of Origin:  C57BL/6NTac
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 Protein and 4 guide sequences AACATCCAGAATACCATGCGGGG, AGGTATCTAGGCGTCTAGGCAGG, TGAGTTAGGGATGAGTGTTCTGG, CCATGCGGGGTCTGTCCCCGAGT, which resulted in a Exon Deletion. (J:265051)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sv2a Mutation:  37 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory