Appem1H
Endonuclease-mediated Allele Detail
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Symbol: |
Appem1H |
Name: |
amyloid beta precursor protein; endonuclease-mediated mutation 1, Harwell |
MGI ID: |
MGI:6384251 |
Synonyms: |
APP-MABH-EM1-B6N |
Gene: |
App Location: Chr16:84751236-84972187 bp, - strand Genetic Position: Chr16, 46.92 cM, cytoband C3-qter
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Alliance: |
Appem1H page
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Allele Type: |
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Endonuclease-mediated (Humanized sequence) |
Mutation: |
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Nucleotide substitutions
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Mutation details: CRISPR-targeting produced the amino acid substitutions glycine for arginine at position 601 (G601R), tyrosine for phenylalanine at position 606 (F606Y), and histidine for arginine (R609H).
(J:90559)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any App Mutation: |
89 strains or lines available
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Original: |
J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013; |
All: |
1 reference(s) |
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