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Sox2em1(IMPC)Mbp
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Sox2em1(IMPC)Mbp
Name: SRY (sex determining region Y)-box 2; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI ID: MGI:6382406
Gene: Sox2  Location: Chr3:34704554-34706610 bp, + strand  Genetic Position: Chr3, 16.93 cM, cytoband A2-B
Mutation
origin
Strain of Origin:  C57BL/6NCrl
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Deletion
 
Mutation detailsThis allele from IMPC was generated at UC Davies by injecting CAS9 Protein and 2 guide sequences CCGCAGCGAAACGACAGCTGCGG, ACTAATCACAACAATCGCGGCGG, which resulted in a Whole-gene deletion. (J:265051)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox2 Mutation:  47 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory