Ywhah^tm1.2Cya
Targeted Allele Detail

Summary

• Symbol: Ywhah^tm1.2Cya
• Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; targeted mutation 1.2, Cyagen Biosciences
• MGI ID: MGI:6380693
• Synonyms: Ywhah^tm1.2Cgen
• Gene: Ywhah Location: Chr5:33176160-33185310 bp, + strand Genetic Position: Chr5, 17.42 cM, cytoband B1
• Alliance: Ywhah^tm1.2Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:281426
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette and left exon 2 floxed. Cre-mediated recombination removed exon 2. (J:281426)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ywhah Mutation: 30 strains or lines available

References

• Original: J:281426 Eisa AA, et al., YWHA (14-3-3) protein isoforms and their interactions with CDC25B phosphatase in mouse oogenesis and oocyte maturation. BMC Dev Biol. 2019 Oct 22;19(1):20
• All: 2 reference(s)