Usp48^tm2.1Dfre
Targeted Allele Detail

Summary

• Symbol: Usp48^tm2.1Dfre
• Name: ubiquitin specific peptidase 48; targeted mutation 2.1, Dorothy M French
• MGI ID: MGI:6379600
• Synonyms: Usp48^fl
• Gene: Usp48 Location: Chr4:137321079-137385842 bp, + strand Genetic Position: Chr4, 70.0 cM
• Alliance: Usp48^tm2.1Dfre page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279204
• Parent Cell Line: C2 (Nagy) (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3, encoding catalytic Cys98. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exon 3 floxed. (J:279204)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp48 Mutation: 218 strains or lines available

References

• Original: J:279204 Ferrando RE, et al., Immunohistochemical detection of FLAG-tagged endogenous proteins in knock-in mice. J Histochem Cytochem. 2015 Apr;63(4):244-55
• All: 1 reference(s)