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Tg(Krt13-cre)139Gaff
Transgene Detail
Nomenclature
Symbol: Tg(Krt13-cre)139Gaff
Name: transgene insertion 139, Sarah L Gaffen
MGI ID: MGI:6379001
Synonyms: K13CRE
Transgene: Tg(Krt13-cre)139Gaff  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe mouse Krt13 promoter derived from BAC RP23-10A2 constitutively drives expression of an NLS (nuclear localization signal)-cre cassette in these transgenic mice. Four PCR+ founders were identified, and tissues were evaluated. Line 139 where Cre expression most closely paralleled the known expression pattern of Krt13 was used for all experiment. (J:281520)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt13     Summary of all recombinase alleles driven by Krt13. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:281520 Conti HR, et al., IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis. Cell Host Microbe. 2016 Nov 9;20(5):606-617
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory