Slc25a44^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc25a44^em1(IMPC)J
• Name: solute carrier family 25, member 44; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6376222
• Gene: Slc25a44 Location: Chr3:88317805-88332446 bp, - strand Genetic Position: Chr3, 38.82 cM
• Alliance: Slc25a44^em1(IMPC)J page
• IMPC: Slc25a44 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTAGCTTTACCACAAAGTCG AND GGTGAGGAATGATTTCAGAA, which resulted in a 1060 bp deletion beginning at Chromosome 3 position 88,420,282 bp and ending after 88,421,341 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000980176 (exon 2) and 422 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 15 and early truncation 43 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Slc25a44 Mutation: 10 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)